The Endocannabinoid System and Spermatogenesis
نویسندگان
چکیده
منابع مشابه
The Endocannabinoid System and Spermatogenesis
Spermatogenesis is a complex process in which male germ cells undergo a mitotic phase followed by meiosis and by a morphogenetic process to form mature spermatozoa. Spermatogenesis is under the control of gonadotropins, steroid hormones and it is modulated by a complex network of autocrine and paracrine factors. These modulators ensure the correct progression of germ cell differentiation to for...
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Objective(s) Fatty acid is amide hydrolase which reduce endogenous anandamide. Transient receptor potential vanilloid-1 (TRPV1) channels have been reported to have a role in the modulation of anxiety-like behaviors in rodents. In the present study, the effects of either endocannabinoid system or TRPV1 channels and their possible interaction on anxiety-like behaviors of the rats were explored. ...
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The therapeutic potential of cannabinoids has been the topic of extensive investigation following the discovery of cannabinoid receptors and their endogenous ligands. Cannabinoid receptors and their endogenous ligands are present at supraspinal, spinal and peripheral levels. Cannabinoids suppress behavioral responses to noxious stimulation and suppress nociceptive processing through activation ...
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Introduction One of the environmental factors that precipitates and exacerbates mental illnesses, including depression, anxiety disorders, and substance abuse, is repeated life stress. For example, homotypic stressors that occur on a daily basis, such as poverty or medical problems, are associated with increased depressive symptoms [1]. Not everyone exposed to stress has pathological consequenc...
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The human body possesses specific binding sites on the surface of many cell types for cannabinoids, and our body produces several endocannabinoids, fatty acid derivatives that bind to these cannabinoid receptors (CB) and activate them. CB receptors and endocannabinoids together constitute the endocannabinoid system. Some phytocannabinoids, cannabinoids of the cannabis plant, and a multitude of ...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2013
ISSN: 1664-2392
DOI: 10.3389/fendo.2013.00192